Magnesium Sulfate
| Class:
Electrolyte Mechanism of action: Reduces striated muscle contractions and blocks peripheral neuromuscular transmission by reducing ACh release at the myoneural junction, manages seizures in toxemia of pregnancy, induces uterine relaxation, can cause bronchodilation after beta-agonists and anticholinergics have been used Indications: Seizures of eclampsia, torsade de pointes, hypomagnesemia, Class IIa agent for v-fib/pulseless v-tach that is refractory to lidocaine Contraindications: Heart blocks, myocardial damage. Adverse reactions: CNS depression, facial flushing, diaphoresis, depressed reflexes, circulatory collapse, hypotension Drug Interactions: May enhance effects of other CNS depressants, serious changes in overall cardiac function may occur with cardiac glycosides. |
How
Supplied: 10%, 12.5%,
50% solution in 40, 80, 100, and 125mg/mL |
Meperidine (Demerol)
| Class:
Opioid analgesic Mechanism of action: Synthetic opioid agonist that acts on opioid receptors to produce analgesia, euphoria, respiratory and physical depression; a schedule II drug with potential for physical dependency and abuse Indications: Analgesia for moderate to severe pain. Contraindications: Hypersensitivity to narcotic agents, diarrhea caused by poisoning, patients taking MAOIs, during labor or delivery of a premature infant, undiagnosed abdominal pain or head injury Adverse reactions: Respiratory depression, sedation, apnea, circulatory depression, arrhythmias, shock euphoria, delirium, agitation, hallucinations, visual disturbances, coma, seizures, headache, facial flushing, increased ICP, N/V Drug Interactions: DO NOT give concurrently with MAOIs (even with a dose in the last 14 days). Exacerbates CNS depression when given with these meds. |
How
Supplied: 50/mL in 1-mL
prefilled syringes and Tubex |
Methylprednisolone (Solu-Medrol)
| Class:
Anti-inflammatory glucocorticoid Mechanism of action: Synthetic corticosteroid that suppresses acute and chronic inflammation; potentiates vascular smooth muscle relaxation by beta-adrenergic agonists. Indications: Acute spinal cord trauma, anaphylaxis, bronchodilator for unresponsive asthma. Contraindications: Premature infants, systemic fungal infections; use with caution in patients with GI Bleeds Adverse reactions: Headache, hypertension, sodium and water retention, CHF, hypokalemia, alkalosis, peptic ulcer disease, N/V Drug Interactions: Hypoglycemic responses to insulin and hypoglycemic agents may be blunted. Potassium-depleting agents may exacerbate hypokalemic effects |
How
Supplied: 40, 125, 300,
and 1,000mg vials |
Midazolam (Versed)
| Class:
Short-acting benzodiazepine (benzo's) CNS depressant Mechanism of action: Anxiolytic and sedative properties similar to other benzo's, memory impairment. Indications: Sedation, Anxiolytic prior to ET or NT intubation; administer for conscious sedation Contraindications: Glaucoma, shock, coma, ETOH, overdose, depressed vital signs, concomitant use with other CNS depressants, barbiturates, narcotics Adverse reactions: Hiccough, cough, oversedation, N/V, injection site pain, headache, blurred vision, hypotension, respiratory depression, and arrest. Drug Interactions: Should no be used with patients who have taken a CNS depressants |
How
Supplied: 2,5,10mL
vials(1mg/mL); 1,2,5, 10mL vials(5mg/mL) |
